“Fruiting liquid” of mushroom-forming fungi, a novel source of bioactive compounds – Fruiting-body inducer and HIF and Axl inhibitors 査読

Wu J, Uchida K, Yoshikawa A, Hashimoto M, Kondo M, Nihei K, Ishii M, ... Kawagishi H.

J. Agric. Food Chem.   71   13338   2023年

Chemical synthesis and tyrosinase inhibitory activity of resorcinol alkyl glucosides, hydroxyalkyl resorcinols, and alkyl resorcinols 査読

Ishioka W, Nihei K

J. Mol. Struct.   1268   133668   2022年

Intracellular oxidation of methyl p-coumarate is involved in anti-melanogenic and cytotoxic activities against melanoma cells 査読 国際共著

Satooka H, Nihei K, Kubo I

Phytochem. Lett.   50   89 - 94   2022年

Comprehensive analysis and biological characterization of venom components from solitary scoliid wasp Campsomeriella annulata annulate 査読

Alberto-Silva C, Portaro FCV, Kodama RT, Pantaleão HQ, Inagaki H, Nihei K, Konno K

Toxins   13   885   2021年

Isolation and characterization of FMRFamide-like peptides in the venoms of solitary sphecid wasps 査読

Nihei K, Peigneur S, Tytgat J, Lange AB, Konno K

Peptides   142   170575   2021年

Novel neuroprotective peptides in the venom of the solitary scoliid wasp Scolia decorata ventralis 査読

Alberto-Silva C, Portaro FCV, Kodama RT, Pantaleão HQ, Rangel M, Nihei K, Konno K

J. Venom Anim. Toxins incl. Trop. Dis.   27   e20200171   2021年

Synthesis, structural revision, and tyrosinase inhibitory activity of proposed phloretin-4-O-β-D-glucopyranoside from Homalium stenophyllum 査読

Shimakage R, Nihei K

Nat. Prod. Res.   36   1803 - 1811   2022年

Comprehensive analysis of peptides and low molecular weight components of the giant ant Dinoponera quadriceps venom 査読

Rádis-Baptista G, Dodou HV, Prieto-da-Silva ÁRB, Zaharenko AJ, Kazuma K, Nihei K, Inagaki H, Mori-Yasumoto K, Konno K

Biol. Chem.   401   945 - 954   2020年

Tyrosinase inhibition by 4-substituted benzaldehydes with electron-withdrawing groups 査読

Nihei K, Kubo I

Appl. Biochem. Biotechnol.   191   1711 - 1716   2020年

Systematic approach to the chemical synthesis of arabidopyrones, the unique α-pyrones of Arabidopsis metabolites 査読

Matsunoto T, Harima S, Weng J, Nihei K

Synth. Commun.   50   2981 - 2987   2020年

Molecular design of potent, hydrophilic tyrosinase inhibitors based on the natural dihydrooxyresveratrol skeleton 査読

Tanaka Y, Suzuki M, Kodachi Y, Nihei K

Carbohydr. Res.   472   42 - 49   2019年

Benzonitriles as tyrosinase inhibitors with hyperbolic inhibition manner 査読

Nihei K, Kubo I

Int. J. Biol. Macromol.   133   929 - 932   2019年

Total synthesis of apios isoflavones and investigation of their tyrosinase inhibitory activity 査読

Asebi N, Nihei K

Tetrahedron   75   130589   2019年

Extraction of strawberry leaves with supercritical carbon dioxide and entrainers: Antioxidant capacity, total phenolic content, and inhibitory effect on uric acid production of the extract 査読

Sato T, Ikeya Y, Adachi S, Yagasaki K, Nihei K, Itoh N

Food Bioprod. Process.   117   160 - 169   2019年

Resorcinol alkyl glucosides as potent tyrosinase inhibitors 査読

Ishioka W, Oonuki S, Iwadate T, Nihei K

Bioorg. Med. Chem. Lett.   29   313 - 316   2019年

Chemical synthesis and tyrosinase-inhibitory activity of isotachioside and its related glycosides 査読

Matsumoto T, Nakajima T, Iwadate T, Nihei K

Carbohydr. Res.   465   22 - 28   2018年

Effect of temperature and pressure on the extraction of strawberry receptacles with a mixture of supercritical carbon dioxide and entrainers 査読

Sato T, Fukuda F, Nihei K, Itoh N

J. Supercrit. Fluids   130   23 - 29   2017年

Substituent effect of benzaldehydes on tyrosinase inhibition 査読

Nihei K, Kubo I

Plant Physiol. Biochem.   112   278 - 282   2017年

Anti-hyperuricemic effect of taxifolin in cultured hepatocytes and model mice 査読

Adachi S, Nihei K, Ishihara Y, Yoshizawa F, Yagasaki K

Cytotechnology   69   329 - 336   2017年

Chemical synthesis, redox transformation, and identification of sonnerphenolic C, an antioxidant in Acer nikoense 査読

Iwadate T, Nihei K

Bioorg. Med. Chem. Lett.   27   1799 - 1802   2017年

Peptidomic analysis of the venom of the solitary bee Xylocopa appendiculata circumvolans 査読

Kazuma K, Ando K, Nihei K, Wang X, Rangel M, Franzolin MR, Mori-Yasumoto K, Sekita S, Kadowaki M, Satake M, Konno K

J. Venom Anim. Toxins incl. Trop. Dis.   23   40   2017年

Dihydroresveratrol cellobioside and xylobioside as effective melanogenesis activators 査読

Oode C, Shimada W, Yokota M, Yamada Y, Nihei K

Carbohydr. Res.   436   45 - 49   2016年

Peptide toxins in solitary wasp venoms 査読

Konno K, Kazuma K, Nihei K

Toxins   8   114   2016年

Cloning and functional analysis of three chalcone synthases from the flowers of safflowers Carthamus tinctorius 査読

Shinozaki J, Kenmoku H, Nihei K, Masuda K, Noji M, Konno K, Asakawa Y, Kazuma K

Nat. Prod. Commun.   11   787 - 790   2016年

Inhibitory effects of cardols and related compounds on superoxide anion generation by xanthine oxidase 査読

Masuoka N, Nihei K, Maeta A, Yamagiwa Y, Kubo I

Food Chem.   166   270 - 274   2015年

Rhododendrol glycosides as stereospecific tyrosinase inhibitors 査読

Iwadate T, Nihei K

Bioorg. Med. Chem.   23   6650 - 6658   2015年

Synthesis of dihydroresveratrol glycosides and their effects on B16F0 melanoma cells 査読

Oode C, Shimada W, Izutsu Y, Yokota M, Iwadate T, Nihei K

Eur. J. Med. Chem.   87   862 - 867   2014年

Chemical synthesis and tyrosinase inhibitory activity of rhododendrol glycosides 査読

Iwadate T, Kashiwakura Y, Masuoka N, Yamada Y, Nihei K

Bioorg. Med. Chem. Lett.   24   122 - 125   2014年

Stereochemical investigation and total synthesis of inuloidin, a biologically active sesquiterpenoid from Heterotheca inuloides 査読

Kamatani J, Iwadate T, Tajima R, Kimoto H, Yamada Y, Masuoka N, Kubo I, Nihei K

Tetrahedron   70   3141 - 3145   2014年

Identification of nitric oxide generation-stimulative principle in Scutellariae radix 査読

Chen Z, Nihei K, Tanaka H, Uda Y, Kabuyama Y

Biosci. Biotechnol. Biochem.   77   657 - 659   2013年

Absolute stereochemistry of altersolanol A and alterporriols. 査読

Kanamaru S, Honma M, Murakami T, Tsushima T, Kudo S, Tanaka K, Nihei K, Nehira T, Hashimoto M

Chirality   24   137 - 146   2012年

ニワトリ角膜におけるコレステロールエステルとアポリポタンパク質A-I 査読

谷優里，塚原直樹，蕪山由己人，二瓶賢一，杉田昭栄

日本家禽学会誌   49   J1 - J6   2012年

Novel isoflavone diglycoside in groundnut (Apios americana Medik) 査読

Nara K, Nihei K, Ogasawara Y, Koga H, Kato Y

Food Chem.   124   703 - 710   2011年

High levels of apolipoproteins found in the soluble fraction of avian cornea 査読

Tsukahara N, Tani Y, Nihei K, Kabuyama Y, Sugita S

Exp. Eye Res.   92   432 - 435   2011年

Chemical and biological characterization of four new linear cationic cytolytic peptides from the venoms of two solitary eumenine wasps 査読

Rangel M, Cabrera MPS, Kazuma K, Ando K, Wang X, Kato M, Nihei K, Hirata IY, Cross TJ, Garcia AN, Faquim-Mauro EL, Franzolin MR, Fuchino H, et al

Toxicon   47   1081 - 1092   2011年

Synthesis and evaluation of bibenzyl glycosides as potent tyrosinase inhibitors 査読

Tajima R, Oozeki H, Muraoka S, Tanaka S, Motegi Y, Nihei K

Eur. J. Med. Chem.   46   1374 - 1381   2011年

Genetic replacement of tesB with PTE1 affects chain-length proportions of 3-hydroxyalkanoic acids produced through β-oxidation of oleic acid in Escherichia coli 査読

Seto Y, Kang J, Ming L, Habu N, Nihei K, Ueda S, Maeda I

J. Biosci. Bioeng.   110   392 - 396   2010年

Four analogues of spiroleptosphol isolated from Leptosphaeria doliolum 査読

Murakami T, Tsushima T, Takada N, Tanaka K, Nihei K, Miura T, Hashimoto M

Bioorg. Med. Chem.   17   492 - 495   2009年

Sweet and bitter constituents of Wilbrandia species 査読

Ochi M, Moriyama K, Ohmae K, Fukuyama Y, Nihei K, Kubo I

Food Chem.   115   61 - 65   2009年

Absorption of hydroxyproline-containing peptides in vascularly perfused rat small intestine in situ 査読

Liu C, Sugita K, Nihei K, Yoneyama K, Tanaka H

Biosci. Biotechnol. Biochem.   73   1741 - 1747   2009年

Molecular design of potent tyrosinase inhibitors having the bibenzyl skeleton 査読

Oozeki H, Tajima R, Nihei K

Bioorg. Med. Chem. Lett.   18   5252 - 5254   2008年

Design and evaluation of anacardic acid derivatives as anti-cavity agents 査読

Green IR, Tocoli FE, Lee SH, Nihei K, Kubo I

Eur. J. Med. Chem.   43   1315 - 1320   2008年

Insect growth inhibitory activity and cytotoxicity of tannic acid from Gallae rhois 査読

Kubo I, Hori I, Nihei K, Satooka H, Céspedes CL, Calderón JS

Biopestic. Int.   4   6 - 14   2008年

Antimicrobial activity of anethole and related compounds from aniseed 査読

Kubo I, Fujita K, Nihei K

J. Sci. Food Agric.   88   242 - 247   2008年

Effects of quercetin on mushroom tyrosinase and B16-F10 melanoma cells 査読

Kubo I, Nitoda T, Nihei K

Molecules   12   1045 - 1056   2007年

Molecular design of anti-MRSA agents based on the anacardic acid scaffold 査読

Green IR, Tocoli FE, Lee SH, Nihei K, Kubo I

Bioorg. Med. Chem.   15   6236 - 6241   2007年

Manicoba, a quercetin-rich Amazonian dish 査読

Kubo I, Masuoka N, Nihei K, Burgheim B

J. Food Compos. Anal.   19   579 - 588   2006年

An RNA polymerase inhibitor, cyclothiazomycin B1, and its isomer 査読

Hashimoto M, Murakami T, Funahashi K, Tokunaga T, Nihei K, Okuno T, Kimura T, Naoki H, Himeno H

Bioorg. Med. Chem.   14   8259 - 8270   2006年

Musidunin and musiduol, insect antifeedants from Croton jatrophoides 査読

Nihei K, Asaka Y, Mine Y, Yamada Y, Iigo M, Yanagisawa T, Kubo I

J. Nat. Prod.   69   975 - 977   2006年

An efficient and versatile synthesis of all structural types of acylpolyamine spider toxins 査読

Nihei K, Kato MJ, Yamane T, Konno K

Tetrahedron   69   8335 - 8350   2006年

Xanthine oxidase inhibitory activity of alkyl gallates 査読

Masuoka N, Nihei K, Kubo I

Mol. Nutr. Food Res.   50   725 - 731   2006年

Biological activities of 2α-substituted analogues of 1α,25-dihydroxyvitamin D₃ in transcriptional regulation and human promyelocytic leukemia (HL-60) cell proliferation and differentiation 査読

Takahashi E, Nakagawa K, Suhara Y, Kittaka A, Nihei K, Konno K, Takayama H, Ozono K, Okano T

Biol. Pharm. Bull.   29   2246 - 2250   2006年

The antiepileptic activity of JSTX-3 is mediated by N-methyl-D-aspartate receptors in human hippocampal neurons 査読

Salamoni SD, Costa JC, Palma MS, Konno K, Nihei K, Neto AEP, Venturin GT, Travares AA, Abreu DS, Breda RV

NeuroReport   16   1869 - 1873   2005年

Enantioselective synthesis of four isomers of 3-hydroxy-4-methyltetradecanoic acid, the constituent of antifungal cyclodepsipeptides W493 A and B 査読

Nihei K, Hashimoto K, Miyairi K, Okuno T

Biosci. Biotechnol. Biochem.   69   231 - 234   2005年

Pachyelasides A-D, novel molluscicidal triterpene saponins from Pachyelasma tessmannii 査読

Nihei K, Ying BP, Murakami H, Matsuda N, Hashimoto M, Kubo I

J. Agric. Food Chem.   53   608 - 613   2005年

Insect antifeedants from Croton jatrophoides: Structures of zumketol, zumsenin, and zumsenol 査読

Nihei K, Asaka Y, Mine Y, Kubo I

J. Nat. Prod.   68   244 - 247   2005年

Antiepileptic effect of acylpolyaminetoxin JSTX-3 on rat hippocampal CA1 neurons in vitro 査読

Salamoni SD, Costa JC, Palma MS, Konno K, Nihei K, Travaras AA, Abreu DS, Venturin GT, Cunha FB, Oliveira RM, Breda RV

Brain Res.   1048   170 - 176   2005年