Organization
President, Executive Director Vice President
Institute for Social Innovation and Cooperation Director General
Institute for Social Innovation and Cooperation Director General
Title
Vice President
Contact information
YOSHIZAWA Fumiaki
Degree
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博士（農学） ( 東京農工大学 )
Research Areas
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Others / Others / 環境生理学
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Life Science / Sports sciences / アミノ酸の代謝調節因子としての作用の解析
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Life Science / Food sciences / 遺伝子発現の翻訳調節機構の解明
Education
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Tokyo University of Agriculture and Technology 連合農学研究科
- 1994.5
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Tokyo University of Agriculture and Technology 農学研究科
- 1991.3
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Tokyo University of Agriculture and Technology 農学部 農芸化学科
- 1989.3
Research History
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Morioka Junior College Iwate Prefecutural University Lecturer
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Morioka Junior College Iwate Prefecutural University Research Assistant
Professional Memberships
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American Society for Nutrition
2015.4 - Present
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日本アミノ酸学会
2007.4 - Present
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日本畜産学会
2000.4 - Present
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Japan Society of Nutrition and Food Science
1990.4 - Present
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Japan Society for Bioscience, Biotechnology, and Agrochemistry
1989.4 - Present
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The American Physiological Society
Studying abroad experiences
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1999.8 - 1999.9 The Pennsylvania State University College of Medicine
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1996.8 - 1997.9 The Pennsylvania State University College of Medicine
Papers
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Tiliroside Suppresses Uric Acid Production in Hepatocytes and Attenuates Purine-Induced Hyperuricemia in Male ICR Mice Reviewed
Shin-ichi Adachi, Shinji Kondo, Yusuke Sato, Fumiaki Yoshizawa, Kazumi Yagasaki
molecules 30 ( 19 ) 3914 2025.9
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Analysis of the Stimulative Effect of Arginine on Translation Initiation of Protein Synthesis in Skeletal Muscle Reviewed
Daisuke Suzuki, Yuki Takami, Yusuke Sato, Yuka Toyoshima, Fumiaki Yoshizawa
Nutrients 17 ( 18 ) 2981 2025.9
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Deletion of IRS-1 leads to growth failure and insulin resistance with downregulation of liver and muscle insulin signaling in rats Reviewed
Yuka Toyoshima, Katsuyuki Nakamura, Yusuke Taguchi, Reiko Tokita, Shiho Takeuchi, Hayato Osawa, Naomi Teramoto, Hidetoshi Sugihara, Fumiaki Yoshizawa
Sci Rep 15 ( 1 ) 649 2025.1
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Effects of two types of Coccomyxa sp. KJ on in vitro ruminal fermentation, methane production, and the rumen microbiota Reviewed
Yoshiaki Sato, Honoka Shioya, Yuma Uda, Hiroshi Asano, Yoshikazu Nagao, Hitoshi Kuno, Fumiaki Yoshizawa
PLoS One 19 ( 8 ) e0308646 2024.8
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Impact of rumen microbiome on cattle carcass traits Reviewed
Yoshiaki Sato, Ruki Sato, Emiko Fukui, Fumiaki Yoshizawa
Sci Rep 14 ( 1 ) 6064 2024.3
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Antidiabetic Effect of Urolithin A in Cultured L6 Myotubes and Type 2 Diabetic Model KK-Ay/Ta Mice with Glucose Intolerance Reviewed
Shinji Kondo, Shin-Ichi Adachi, Wataru Komatsu, Fumiaki Yoshizawa, Kazumi Yagasaki
Curr Issues Mol Biol 46 ( 2 ) 1078 - 1090 2024.1
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Trial Analysis of the Relationship between Taste and Biological Information Obtained While Eating Strawberries for Sensory Evaluation Reviewed
Keisuke Maeda, Ren Togo, Takahiro Ogawa, Shin-Ichi Adachi, Fumiaki Yoshizawa, Miki Haseyama
Sensors 22 ( 23 ) 9496 2022.12
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Functional analysis reveals that Tinagl1 is required for normal muscle development in mice through the activation of ERK signaling Reviewed
Yoriko Sato, Keisuke Kawashima, Emiko Fukui, Hiromichi Matsumoto, Fumiaki Yoshizawa, Yusuke Sato
Biochim Biophys Acta Mol Cell Res 1869 ( 9 ) 119294 2022.9
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Analysis of the Stimulative Effect of Tryptophan on Hepatic Protein Synthesis in Rats Reviewed
Kodwo Amuzuah Obeng, Shinji Mochizuki, Shinichiro Koike, Yuka Toyoshima, Yusuke Sato, Fumiaki Yoshizawa
J Nutr Sci Vitaminol 68 ( 4 ) 312 - 319 2022.8
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Antidiabetic Effect of Taxifolin in Cultured L6 Myotubes and Type 2 Diabetic Model KK-Ay/Ta Mice with Hyperglycemia and Hyperuricemia Reviewed
Shinji Kondo, Shin-Ichi Adachi, Fumiaki Yoshizawa, Kazumi Yagasaki
Curr Issues Mol Biol 43 ( 3 ) 1293 - 1306 2021.9
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Quercetin enhances fatty acid β-oxidation by inducing lipophagy in AML12 hepatocytes
Misato Fukaya, Yoriko Sato, Shinji Kondo, Shin-Ichi Adachi, Fumiaki Yoshizawa, Yusuke Sato
Heliyon 7 ( 6 ) e07324 2021.6
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Energy metabolism profile of the effects of amino acid treatment on hepatocytes: Phenylalanine and phenylpyruvate inhibit glycolysis of hepatocytes Reviewed
Reiko Suzuki, Yoriko Sato, Misato Fukaya, Daisuke Suzuki, Fumiaki Yoshizawa, Yusuke Sato
Nutrition 82 111042 2021.2
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Antihyperuricemic Effect of Urolithin A in Cultured Hepatocytes and Model Mice Reviewed
Shin-Ichi Adachi, Kazunori Sasaki, Shinji Kondo, Wataru Komatsu, Fumiaki Yoshizawa, Hiroko Isoda, Kazumi Yagasaki
Molecules 25 ( 21 ) 5136 2020.11
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An Increase in Liver Polyamine Concentration Contributes to the Tryptophan-Induced Acute Stimulation of Rat Hepatic Protein Synthesis
Shinichiro Koike, Yukihito Kabuyama, Kodwo Amuzuah Obeng, Kunio Sugahara, Yusuke Sato, Fumiaki Yoshizawa
Nutrients 12 ( 9 ) 2665 2020.9
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Data on the proliferation and differentiation of C2C12 myoblast treated with branched-chain ketoacid dehydrogenase kinase inhibitor. Reviewed
Yoriko Sato, Hayato Tate, Fumiaki Yoshizawa, Yusuke Sato
Data Brief. 31 105766 2020.5
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Prolyl-hydroxyproline, a collagen-derived dipeptide, enhances hippocampal cell proliferation, which leads to antidepressant-like effects in mice. Reviewed
Dai Nogimura Takafumi Mizushige Yuki Taga Fumiaki Yoshizawa Yukihito Kabuyama
2020.4
Books
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タンパク質・アミノ酸の科学
岸恭一, 西村敏英 監修,日本必須アミノ酸協会 編（ Role： Joint author , Area： 第３章 タンパク質合成とアミノ酸）
工業調査会 2007.3 （ ISBN:9784769371557 ）
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代謝美人でシャッキリ! BCAAで劇的カラダデザイン!
代謝機能向上委員会（ Role： Supervisor (editorial)）
幻冬社ルネッサンス 2005.6 （ ISBN:9784779000027 ）
MISC
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Notable functions of branched chain amino acids as a biological regulator
67 ( 6 ) 238 - 244 2009
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代謝調節因子として注目される分岐鎖アミノ酸
吉澤史昭 長澤孝志
化学と生物 45 ( 3 ) 203 - 210 2007.3
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Regulation of protein synthesis by branched-chain amino acids in vivo. Reviewed
313 417 - 422 2004
Awards for Research Activities
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森永賞
2009.6 財団法人 森永奉仕会 ホエイタンパク質の分岐鎖アミノ酸供給源としての有用性の評価
吉澤史昭
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奨励賞
2002.5 社団法人 日本栄養・食糧学会 体タンパク質合成の翻訳段階調節に関する栄養生化学的研究
吉澤史昭
Research Projects
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アルギニンのタンパク質合成促進シグナル分子としての機能解析
Grant number：18K05501 2018.4 - 2022.3
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Scientific Research(C)
Authorship：Principal investigator
Grant amount：\4290000 （ Direct Cost: \3300000 、 Indirect Cost：\990000 ）
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トリプトファンの肝タンパク質合成促進機能の解析と摂取の有効性・安全性の評価
Grant number：22380071 2010.4 - 2013.3
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Scientific Research(B)
Grant amount：\18200000 （ Direct Cost: \3400000 、 Indirect Cost：\1020000 ）
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血糖値低下を誘導するイソロイシンの糖代謝調節シグナル分子としての機能の解析
Grant number：19580133 2007 - 2008
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Scientific Research(C)
Authorship：Principal investigator
Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）
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分岐鎖アミノ酸の血糖値低下作用の機構解析とその糖尿病治療への寄与
Grant number：17580104 2005 - 2006
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Scientific Research(C)
Authorship：Principal investigator
Grant amount：\3500000 （ Direct Cost: \1900000 、 Indirect Cost：\1600000 ）
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シグナル因子としてのアミノ酸のタンパク質合成翻訳開始促進作用の解析
Grant number：14760078 2002 - 2004
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Young Scientists(B)
Authorship：Principal investigator
Grant amount：\3400000 （ Direct Cost: \3400000 ）
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食餌摂取に応答する組織蛋白質合成の翻訳開始調節機構の解析
Grant number：10760085 1998 - 1999
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Encouragement of Scientists
Authorship：Principal investigator
Grant amount：\2000000 （ Direct Cost: \2000000 ）
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トリプトファンの肝タンパク質合成促進シグナルの作用点の解明
Grant number：22K05472 2022.4 - 2025.3
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Scientific Research(C)
Authorship：Principal investigator
Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）
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ロイシンのタンパク質合成促進刺激に対する応答の違いを利用した筋肉タイプ別萎縮抑制
Grant number：15K07423 2015.4 - 2018.3
Grants-in-Aid for Scientific Research (KAKENHI) Grant-in-Aid for Scientific Research(C)
Authorship：Principal investigator
Grant amount：\4940000 （ Direct Cost: \3800000 、 Indirect Cost：\1140000 ）
Class
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健康のためなら死んでもいい!? G560022
2022 （ University ）